In the quest for sustainable and biocompatible materials, researchers have been exploring the properties and applications of polydopamine (PDA), a biopolymer with a wide range of unique characteristics. PDA has been found to possess free-radical scavenging, high photothermal conversion efficiency, biocompatibility, biodegradability, and excellent fluorescent and theranostic capacity, making it an attractive material for various biomedical applications
Physicochemical and Functional Properties
PDA’s physicochemical properties, including its surface chemistry, have been extensively studied, revealing its potential for drug delivery, biosensing, imaging, and cancer therapy. Its biodegradability and biocompatibility make it an ideal material for in vivo applications, where it can be used to deliver drugs or imaging agents to specific sites in the body.
Recent Advances in Mucosal Drug Delivery
Recent reports have highlighted PDA’s potential as a coating material for nanoparticulate carriers, particularly in mucosal drug delivery applications. This has significant implications for the treatment of diseases affecting mucosal surfaces, such as respiratory, gastrointestinal, and genitourinary tract disorders[3].
Challenges and Future Directions
Despite its promising properties, PDA’s application in mucosal drug delivery faces several challenges, including the need for further research on its interactions with mucosal tissues and the development of scalable manufacturing processes. However, the potential benefits of using PDA in this field make it an area worthy of further exploration
PDA is a biopolymer with unique properties that make it an attractive material for various biomedical applications. Its potential in mucosal drug delivery is particularly promising, and further research is needed to fully exploit its capabilities. As the field of biodegradable polymers continues to evolve, PDA is likely to play an increasingly important role in the development of sustainable and effective biomedical materials
